Abdominal obesity is associated with heart disease in dogs
نویسندگان
چکیده
BACKGROUND The relationship between overall obesity and fat distribution in dogs and the development of heart disease is unclear. In the present study we evaluated the association between overall obesity and fat distribution and clinical heart disease by morphometric and computed tomography (CT)-based measurements. Body condition score (BCS), modified body mass index (MBMI, kg/m2), waist-to-hock-to-stifle distance ratio (WHSDR), waist-to-ilium wing distance ratio (WIWDR), and waist-to-truncal length ratio (WTLR) were compared between dogs with (n = 44) and without (n = 43) heart disease using receiver operating characteristic (ROC) analysis. Intra-abdominal fat (IAF) and subcutaneous fat (SQF) were measured in dogs with (n = 8) and without (n = 9) heart disease at the center of the fourth and fifth lumbar vertebrae by CT. RESULTS BCS was similar between heart disease and healthy groups (3.6 ± 0.2 vs. 3.3 ± 0.1, P = 0.126). The following morphometric measurements were greater in the heart disease group compared with healthy canines: MBMI (65.0 ± 4.5 vs. 52.5 ± 3.7 kg/m2, respectively, P = 0.035); WIWDR (4.1 ± 0.1 vs. 3.1 ± 0.1, P < 0.01); and WTLR (1.25 ± 0.04 vs. 1.05 ± 0.04, P < 0.01). However, there was no significant difference in WHSDR (3.6 ± 0.1 vs. 3.7 ± 0.2, P = 0.875). Interestingly, IAF was significantly increased in dogs with heart disease compared with healthy dogs (23.5 ± 1.5% vs. 19.4 ± 1.2%, P = 0.039) whereas SQF was similar between two groups (35.5 ± 2.7% vs. 38.6 ± 3.5%, P = 0.496). Of the five morphometric indices studied, WIWDR and WTLR provided acceptable discrimination for diagnosing heart disease in dogs, with areas under the ROC curve of 0.778 (95% confidence interval [CI]:0.683-0.874) and 0.727 (95% CI:0.619-0.835), respectively. CONCLUSIONS Our data indicate that abdominal obesity, rather than overall obesity, is associated with heart disease in dogs. Measurements of both WIWDR and WTLR are particular useful for detection of an abdominal obesity in dogs.
منابع مشابه
فراوانی سندرم متابولیک در بیماران بستری در بخش قلب بیمارستان فرشچیان همدان
Background and Objective: The prevalence of metabolic syndrome is on a growing trend. Weight and age are among the most important factors affecting this condition. Evidence is indicative of a relationship between coronary heart diseases and metabolic syndrome. The present study was conducted to determine the prevalence of metabolic syndrome among patients admitted to the Cardiology Department o...
متن کاملتاثیر چاقی، چاقی شکمی و اثر توام هر دو عامل در افزایش فشارخون مردان استان مازندران (مطالعه کسر منتسب به جمعیت): گزارش کوتاه
Background: Hypertension is one of the most important chronic illness worldwide and one the major risk factors for cardiovascular diseases. Obesity and abdominal obesity are risk factors for high blood pressure. Population attributable fraction (PAF) answers the question of how much of the disease burden in a certain population may be reduced if a risk factor like obesity is removed from the po...
متن کاملNo change of IL-1B in the presence of weight loss and abdominal obesity induced by aerobic training without dietary restrictions in obese women
Background: Obesity is associated with systemic inflammation and related with cardiovascular diseases and type 2 diabetes mellitus. In present study, we aimed to assess the influence of aerobic training on pro-inflammatory cytokines IL-1B and in obese women. Methods: To achieve this outcome, thirty sedentary obese women (30 ≤ BMI ≤ 36) aged 30 – 40 years of old were randomly assigned to the ex...
متن کاملThe relation between body mass index and prevalence of ischemic heart disease in type 2 diabetic patients
Background: The transition from communicable to non-communicable diseases has occurred over many years in all countries of the world, even in developing countries. Diabetes and its ischemic heart complication are among the most important second groupe diseases. In recent years, discussions about the role of obesity and weight gain have risen again as a risk factor for both diseases. Our objecti...
متن کاملOverall and Abdominal Obesity Are Inversely Associated With Plasma n-3 Polyunsaturated Fatty Acids in Iranian Adults
Background: Obesity is a common health problem associated with a number of diseases, such as hypertension, cardiovascular disease, hyperlipidemia, diabetes, gout, gall bladder and liver disease, cancer, and depression. The prevalence of obesity is dramatically increasing around the world, especially in the Asia Pacific region. omega-3 is a type of polyunsaturated fatty acids that have several ...
متن کامل